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Table 2 Univariate and multivariate analysis of risk factors for death among 147 solid organ transplant recipients with bloodstream infection by gram negative bacteria

From: Clinical and epidemiological differences and risk factors for death among solid organ transplant recipients with Gram-positive and Gram-negative bloodstream infections

Variables Cases (147) Univariate Multivariate
Death Survival OR IC95 % p OR IC95 % p
N (%) N (%)
Male gender 20 (23.5) 65 (76.5) 1.81 0.76–4.30 0.21    
ICU 11 (52.4) 10 (47.6) 6.6 2.45–17.78 <0.001 2.10 0.54–8.13 0.29
HAIs 15 (25.0) 45 (75.0) 1.74 0.77–3.94 0.21    
Charlson ≥ 3 15 (31.3) 33 (68.7) 2.76 1.20–6.34 0.03 0.68 0.17–2.74 0.59
Co-morb (liver disease) 5 (71.4) 2 (28.6) 12.1 2.21–65.99 0.003 1.45 0.13–15.58 0.76
Co-morb (cancer) 3 (75.0) 1 (25.0) 13.5 1.35–135.0 0.02 6.87 0.40–118.8 0.18
Co-morbidities (≥2) 8 (66.7) 4 (33.3) 10.9 3.00–39.34 <0.01 12.4 1.90–80.35 0.008
Deceased donor 20 (24.1) 63 (75.9) 1.94 0.82–4.61 0.15    
Induction therapy 7 (22.6) 24 (77.4) 1.25 0.48–3.26 0.62    
Acute rejection (AR) 21 (48.8) 22 (51.2) 1.66 0.54–4.24 0.31    
AR-corticosteroids 6 (30.0) 14 (70.0) 1.94 0.67–5.58 0.23    
OB-MMF 5 (11.6) 38 (88.4) 0.44 0.15–1.24 0.17    
OB-Ciclosporine 16 (16.8) 79 (83.2) 0.61 0.27–1.39 0.28    
Double-J 4 (9.8) 37 (90.2) 0.35 0.11–1.08 0.07    
Pre tx dialysis 22 (17.1) 107 (82.9) 0.32 0.11–0.93 0.05 0.58 0.13–2.52 0.47
CMV 4 (20.0) 16 (80.0) 1.02 0.31–3.32 1.00    
Shock 6 (46.2) 7 (53.8) 4.14 1.27–13.45 0.02 0.47 0.08–2.65 0.40
Respiratory failure 15 (62.5) 9 (37.5) 13.0 4.79–35.14 <0.001 13.2 3.07–57.19 0.001
Pre tx diabetes 2 (13.3) 13 (86.7) 0.60 0.13–2.81 0.74    
Inadequate atb 12 (26.7) 33 (73.3) 1.82 0.78–4.21 0.18    
  1. ICU Intensive care unit, HAIs Health-acquired infections, OB onset of BSI, TX transplant, atb antimicrobial