Table 2 Therapeutic category of drugs with intervention reports
From: Drug-related problems and their clinical interventions in a Ghanaian teaching hospital
Drug category | Indication | Number of recommended interventions | *p-value | |
|---|---|---|---|---|
Accepted | Not accepted | |||
Cardiovascular (n = 451[44.3%]) | Anticoagulant | 181 | 22 | 0.053 |
Diuretic | 87 | 9 | <0.001 | |
Calcium channel blockers | 16 | 8 | <0.001 | |
Beta blockers | 20 | 2 | 0.037 | |
ACE inhibitors | 14 | 2 | 0.003 | |
Statin | 17 | 3 | <0.001 | |
Antiplatelet | 15 | 1 | 0.001 | |
Nitrates | 4 | 0 | 0.061 | |
Angiotensin receptor blockers | 3 | 0 | <0.001 | |
Others | 41 | 6 | 0.004 | |
Infections (n = 231[22.7%]) | Antibiotics | 180 | 18 | 0.019 |
Antimalarials | 26 | 0 | 0.009 | |
Antivirals | 5 | 0 | 0.101 | |
Antifungal | 2 | 0 | 0.023 | |
Nutrition (129 [12.7%]) | Iron supplement | 106 | 13 | 0.037 |
Others | 10 | 0 | <0.001 | |
Musculoskeletal (70 [6.9%]) | NSAIDS | 52 | 3 | 0.010 |
Systemic Corticosteroids | 11 | 0 | <0.001 | |
Others | 4 | 0 | <0.001 | |
Central Nervous System (51[5%]) | Opiod analgesic | 39 | 3 | <0.001 |
Sedatives | 6 | 0 | <0.001 | |
Antiepileptic | 2 | 1 | 0.122 | |
Gastro-Intestinal (50 [4.9%]) | Proton pump inhibitor | 27 | 3 | 0.027 |
Antacid | 7 | 0 | 0.980 | |
Laxative | 5 | 0 | 0.001 | |
Others | 6 | 2 | 0.001 | |
Endocrine (14 [1.4%]) | Oral antidiabetics | 9 | 1 | 0.076 |
Insulin | 4 | 0 | 0.001 | |
Respiratory (11 [1.1%]) | Inhalational steroids | 10 | 0 | 0.530 |
Antihistamine | 1 | 0 | 0.890 | |
Others (12 [1.2%]) | 12 | 0 | <0.001 | |